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KMID : 0363220170550020132
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Korean Journal of Dermatology
2017 Volume.55 No. 2 p.132 ~ p.135
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Serum Sickness-like Reaction in a Patient with an Acute Exacerbation of Hepatitis B
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Kim Jong-Baik
Son Hyun-Ok
Chun Sin-Wook
Lee Suk-Young
Ro Byung-In
Cho Han-Kyoung
Choi Han-Gyu
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Abstract
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Serum sickness-like reaction (SSLR) is an abnormal self-limited reaction that can cause fever, myalgia, fatigue, lymphadenopathy, arthralgia, and skin rashes. Its etiology is yet unknown; however, SSLR often develops in patients with hepatitis B and after drug and vaccination administration. SSLR`s typical cutaneous manifestations include polycyclic, erythematous wheal-like or plaque-like lesions. A 47-year-old male hepatitis B carrier visited our emergency department with high fever and multiple annular erythematous plaques with clear centers on his trunk and upper and lower extremities. The patient`s hematologic laboratory results indicated an acute exacerbation of hepatitis B, and his symptoms correlated with those of SSLR. Here, we report a case of SSLR in a patient with an acute exacerbation of hepatitis B with clinical, hematological, and histopathological evidence
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KEYWORD
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Hepatitis B, Serum sickness-like reaction
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